It says the press is a permanent need to determine the genocational sequence of the SARS-COV-2 genotypes of a particular region, as several new options in the Corronavirus concentration occurs in time. He is hanging out. This global panthame is necessary to develop a timely development of antivery diagnostic, monitoring and treatment tools.
Scientists of the genomics center for this purpose are taken from Uzbekistan's first wave of Pandemia from Tashkent region, which is taken from the samples of 32 patients, which were converted to Covid-19 in December, 32 patients. The data of 18 high-quality full genoms from the Sarts-Cov-2 genotypes are located in the international database. Polimorphisms of the nucleotide sequences in sample genome, including coding areas of the coronavirus genuration, have been identified in coding areas of the coronavirus.
The following Coronavirus options were found to be similar to Africa and the Middle East and Europe and North America. So Coronavirus confirms that Uzbekistan entered international travel. That is, the first wave patients are infected with Africa, Middle East, North America, in Africa, European, North America.
Philogenetic analysis 14 full genetic parent (1, 2, 5, 5, 8, 3, 32) g four whole genom samples) and four whole genom samples -Ket group C. (3, 6, 27). A total of 128 mutations consisted of 45 total and 83 unique mutations were identified. Four of them utter the constanism, the sixtight down-STREAM mutulation, 50 are synonymous and 67 are Missenses (meaningless) mutation.
These information is the first coronavirus genuration sequence from the Republic of Uzbekistan, which serves to enrich the database of the global corronitus sequence, serve to conduct future comparative research. Most importantly, the sequence of corronionavirus genotypes obtained in this study serves as a useful source for comparing, diagnostic, monitoring, monitoring, monitoring and treatment of Covid-19 illnesses.
