In accordance with the Decree of the President of the Republic of Uzbekistan dated November 25, 2020 No. PQ-4899 "On comprehensive measures for the development of biotechnology and the improvement of the country's biological safety system" Investments and foreign trade in March of this year ISO 20387:2018 "Biotechnology. Storage of biological samples. General requirements for storage", ISO 20391-1:2018 "Biotechnology - Cell counting - Part 1: General guidelines for cell counting methods", ISO 20391-2:2019 "Biotechnology - Cell counting Part 2: Calculation method experimental design and statistical analysis to determine parameters", ISO 20395:2019 "Biotechnology - Evaluation of the performance of quantitative methods for nucleic acid target sequences. General requirements", ISO 20688-1:2020 "Biotechnology - nucleic acid synthesis - Part 1: Requirements for production and quality control of synthesized oligonucleotides General requirements" standards have been approved.
ISO standards (ISO) are documents that define requirements, specifications, instructions or descriptions for the use of materials, products, processes and services suitable for specific purposes.
Detailed information on the purchase of standards can be found on the website of the Scientific Research Institute of Standardization, Certification and Technical Regulation, uzsti.uz, in the "electronic fund" section.
The Center for Advanced Technologies under the Ministry of Innovative Development is the first organization in Uzbekistan to voluntarily introduce these standards. In particular, the introduction of the ISO 20387:2018 standard and the availability of internationally agreed general guidelines will help improve the quality of stored and transferred biological materials, increase the efficiency of cooperation between biobanks and other organizations, strengthen trust in organizations providing biobanking services, and research and further encourages the development of developments. The requirements of ISO 20387:2018 are intended to be applied by biobanks regardless of their size, type of activity, sources, level of development or complexity. Biobanks were first reported in the late 1990s, and now there is great hope for biobanks that store various biological samples (humans, animals, plants, and microbes), covering all areas of scientific research, from agriculture to personalized medicine. is taking In addition, standard operating procedures are being developed for the development of the technological platform being developed at the Center, taking into account the requirements of ISO 20391-1:2018 and ISO 20391-2, as the results of cell counting will have a wide impact on many aspects of biotechnology, from biological manufacturing to advanced therapies. shows.
The introduction of ISO 20688-1:2020 into laboratory practice improves the efficiency and quality of methods for the quantification of precise nucleic acid sequences (DNA and RNA) using digital (dPCR) or real-time PCR (qPCR) technologies.
It should be noted that these standards can be successfully implemented not only in laboratory practice, but also in the technological process of production of biotechnological products.
